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Structural and mechanistic insights into the latrophilin3 - FLRT3 complex that mediates glutamatergic synapse development
Latrophilins (LPHNs) are adhesion-like G protein coupled receptors implicated in attention-deficit/hyperactivity disorder (ADHD). Recently, LPHN3 was found to regulate excitatory synapse number through trans interactions with fibronectin leucine-rich repeat transmembrane 3 (FLRT3). By isothermal tit...
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| Yayımlandı: | Structure |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930246/ https://ncbi.nlm.nih.gov/pubmed/26235031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.06.022 |
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