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Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors

In order to achieve selective targeting of affinity–ligand coated nanoparticles to the target tissue, it is essential to understand the key mechanisms that govern their capture by the target cell. Next-generation pharmacokinetic (PK) models that systematically account for proteomic and mechanical fa...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Ramakrishnan, N., Tourdot, Richard W., Eckmann, David M., Ayyaswamy, Portonovo S., Muzykantov, Vladimir R., Radhakrishnan, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929918/
https://ncbi.nlm.nih.gov/pubmed/27429783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160260
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