Multivalent Binding of Nanocarrier to Endothelial Cells under Shear Flow

We investigate the effects of particle size, shear flow, and resistance due to the glycocalyx on the multivalent binding of functionalized nanocarriers (NC) to endothelial cells (ECs). We address the much- debated issue of shear-enhanced binding by computing the binding free-energy landscapes of NC...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Jin, Agrawal, Neeraj J., Calderon, Andres, Ayyaswamy, Portonovo S., Eckmann, David M., Radhakrishnan, Ravi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Cellular Biophysics and Electrophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136762/
https://ncbi.nlm.nih.gov/pubmed/21767483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.063
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