SOCS1 suppresses IL-1β-induced C/EBPβ expression via transcriptional regulation in human chondrocytes

CAAT/enhancer-binding protein-beta (C/EBPβ) is a transcription factor that regulates interleukin-1β (IL-1β)-induced catabolic pathways, including the expression of matrix metalloproteinases (MMPs), in chondrocytes. We previously reported that suppressor of cytokine signaling 1 (SOCS1) inhibits IL-1β...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Ha, You-Jung, Choi, Yong Seok, Kang, Eun Ha, Shin, Kichul, Kim, Tae Kyun, Song, Yeong Wook, Lee, Yun Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929694/
https://ncbi.nlm.nih.gov/pubmed/27339399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.47
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