Loading...

The Oligopeptide Permease Opp Mediates Illicit Transport of the Bacterial P-site Decoding Inhibitor GE81112 †

GE81112 is a tetrapeptide antibiotic that binds to the 30S ribosomal subunit and specifically inhibits P-site decoding of the mRNA initiation codon by the fMet-tRNA anticodon. GE81112 displays excellent microbiological activity against some Gram-positive and Gram-negative bacteria in both minimal an...

Full description

Saved in:
Bibliographic Details
Published in:Antibiotics (Basel)
Main Authors: Maio, Alessandro, Brandi, Letizia, Donadio, Stefano, Gualerzi, Claudio O.
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929432/
https://ncbi.nlm.nih.gov/pubmed/27231947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics5020017
Tags: Add Tag
No Tags, Be the first to tag this record!