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Telomere and Telomerase Therapeutics in Cancer
Telomerase is a reverse transcriptase capable of utilizing an integrated RNA component as a template to add protective tandem telomeric single strand DNA repeats, TTAGGG, to the ends of chromosomes. Telomere dysfunction and telomerase reactivation are observed in approximately 90% of human cancers;...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929421/ https://ncbi.nlm.nih.gov/pubmed/27240403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7060022 |
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