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Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo
Telomerase plays a critical role in cancer, prompting the pursuit of various telomerase-based therapeutic strategies. One such strategy, telomerase-interference, exploits the high telomerase activity in cancer cells and reprograms telomerase to encode “toxic” telomeres. To date, telomerase interfere...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820598/ https://ncbi.nlm.nih.gov/pubmed/20124445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0682 |
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