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Phospholipase C δ4 regulates cold sensitivity in mice

KEY POINTS: The cold‐ and menthol‐activated transient receptor potential melastatin 8 (TRPM8) channels are thought to be regulated by phospholipase C (PLC), but neither the specific PLC isoform nor the in vivo relevance of this regulation has been established. Here we identify PLCδ4 as the key PLC i...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Yudin, Yevgen, Lutz, Brianna, Tao, Yuan‐Xiang, Rohacs, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929334/
https://ncbi.nlm.nih.gov/pubmed/27062607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272321
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