Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS) susceptibility in German cohorts with 4888 cases and 10,395 controls. In addition to associations within the major histocompatibility complex (MHC) region, 15 non-MHC loci reached genome-wide significance. Four of these l...

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Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Andlauer, Till F. M., Buck, Dorothea, Antony, Gisela, Bayas, Antonios, Bechmann, Lukas, Berthele, Achim, Chan, Andrew, Gasperi, Christiane, Gold, Ralf, Graetz, Christiane, Haas, Jürgen, Hecker, Michael, Infante-Duarte, Carmen, Knop, Matthias, Kümpfel, Tania, Limmroth, Volker, Linker, Ralf A., Loleit, Verena, Luessi, Felix, Meuth, Sven G., Mühlau, Mark, Nischwitz, Sandra, Paul, Friedemann, Pütz, Michael, Ruck, Tobias, Salmen, Anke, Stangel, Martin, Stellmann, Jan-Patrick, Stürner, Klarissa H., Tackenberg, Björn, Then Bergh, Florian, Tumani, Hayrettin, Warnke, Clemens, Weber, Frank, Wiendl, Heinz, Wildemann, Brigitte, Zettl, Uwe K., Ziemann, Ulf, Zipp, Frauke, Arloth, Janine, Weber, Peter, Radivojkov-Blagojevic, Milena, Scheinhardt, Markus O., Dankowski, Theresa, Bettecken, Thomas, Lichtner, Peter, Czamara, Darina, Carrillo-Roa, Tania, Binder, Elisabeth B., Berger, Klaus, Bertram, Lars, Franke, Andre, Gieger, Christian, Herms, Stefan, Homuth, Georg, Ising, Marcus, Jöckel, Karl-Heinz, Kacprowski, Tim, Kloiber, Stefan, Laudes, Matthias, Lieb, Wolfgang, Lill, Christina M., Lucae, Susanne, Meitinger, Thomas, Moebus, Susanne, Müller-Nurasyid, Martina, Nöthen, Markus M., Petersmann, Astrid, Rawal, Rajesh, Schminke, Ulf, Strauch, Konstantin, Völzke, Henry, Waldenberger, Melanie, Wellmann, Jürgen, Porcu, Eleonora, Mulas, Antonella, Pitzalis, Maristella, Sidore, Carlo, Zara, Ilenia, Cucca, Francesco, Zoledziewska, Magdalena, Ziegler, Andreas, Hemmer, Bernhard, Müller-Myhsok, Bertram
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928990/
https://ncbi.nlm.nih.gov/pubmed/27386562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501678
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