Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer

The functional role of progesterone receptor (PR) and its impact on estrogen signaling in breast cancer remain controversial. In primary ER(+) (estrogen receptor–positive)/PR(+) human tumors, we report that PR reprograms estrogen signaling as a genomic agonist and a phenotypic antagonist. In isolati...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Adv
Autores principales: Singhal, Hari, Greene, Marianne E., Tarulli, Gerard, Zarnke, Allison L., Bourgo, Ryan J., Laine, Muriel, Chang, Ya-Fang, Ma, Shihong, Dembo, Anna G., Raj, Ganesh V., Hickey, Theresa E., Tilley, Wayne D., Greene, Geoffrey L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928895/
https://ncbi.nlm.nih.gov/pubmed/27386569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501924
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares