Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

Direct lineage reprogramming represents a remarkable conversion of cellular and transcriptome states(1–3). However, the intermediates through which individual cells progress are largely undefined. Here we used single-cell RNA-seq(4–7) at multiple time points to dissect direct reprogramming from mous...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Treutlein, Barbara, Lee, Qian Yi, Camp, J. Gray, Mall, Moritz, Koh, Winston, Shariati, Seyed Ali Mohammad, Sim, Sopheak, Neff, Norma F., Skotheim, Jan M., Wernig, Marius, Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928860/
https://ncbi.nlm.nih.gov/pubmed/27281220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18323
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