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ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

We illustrate the use of fluorescence in situ hybridization (FISH) for analysis of ERBB2 oncogene copy number, the level of amplification (here defined as the ratio of ERBB2 copy number to copy number of chromosome 17 centromeres), and the distribution of amplified genes in breast cancer cell lines...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kallioniemi, O P, Kallioniemi, A, Kurisu, W, Thor, A, Chen, L C, Smith, H S, Waldman, F M, Pinkel, D, Gray, J W
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5321
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