ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

We illustrate the use of fluorescence in situ hybridization (FISH) for analysis of ERBB2 oncogene copy number, the level of amplification (here defined as the ratio of ERBB2 copy number to copy number of chromosome 17 centromeres), and the distribution of amplified genes in breast cancer cell lines...

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Bibliographic Details
Main Authors: Kallioniemi, O P, Kallioniemi, A, Kurisu, W, Thor, A, Chen, L C, Smith, H S, Waldman, F M, Pinkel, D, Gray, J W
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49283/
https://ncbi.nlm.nih.gov/pubmed/1351679
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