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ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

We illustrate the use of fluorescence in situ hybridization (FISH) for analysis of ERBB2 oncogene copy number, the level of amplification (here defined as the ratio of ERBB2 copy number to copy number of chromosome 17 centromeres), and the distribution of amplified genes in breast cancer cell lines...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kallioniemi, O P, Kallioniemi, A, Kurisu, W, Thor, A, Chen, L C, Smith, H S, Waldman, F M, Pinkel, D, Gray, J W
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5321
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