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The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer’s disease

Inflammation is becoming increasingly recognized as an important contributor to Alzheimer’s disease (AD) pathogenesis. As a part of the innate immune system, the complement cascade enhances the body’s ability to destroy and remove pathogens and has recently been shown to influence Alzheimer’s associ...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Bonham, Luke W., Desikan, Rahul S., Yokoyama, Jennifer S.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928261/
https://ncbi.nlm.nih.gov/pubmed/27357286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0339-y
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