Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

Patients with chronic obstructive pulmonary disease (COPD) have innate immune dysfunction in the lung largely due to defective macrophage phagocytosis. This deficiency results in periodic bacterial infections that cause acute exacerbations of COPD, a major source of morbidity and mortality. Recent s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Transl Med
Autori principali: Harvey, Christopher J., Thimmulappa, Rajesh K., Sethi, Sanjay, Kong, Xiaoni, Yarmus, Lonny, Brown, Robert H., David, Feller-Kopman, Wise, Robert, Biswal, Shyam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927975/
https://ncbi.nlm.nih.gov/pubmed/21490276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002042
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi