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Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

Patients with chronic obstructive pulmonary disease (COPD) have innate immune dysfunction in the lung largely due to defective macrophage phagocytosis. This deficiency results in periodic bacterial infections that cause acute exacerbations of COPD, a major source of morbidity and mortality. Recent s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Transl Med
मुख्य लेखकों: Harvey, Christopher J., Thimmulappa, Rajesh K., Sethi, Sanjay, Kong, Xiaoni, Yarmus, Lonny, Brown, Robert H., David, Feller-Kopman, Wise, Robert, Biswal, Shyam
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927975/
https://ncbi.nlm.nih.gov/pubmed/21490276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002042
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