Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein

Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles, it is well documented that cyclin-dependent kinase 5 (CDK5), a critical neuronal protein kinase in nervous system development, function, and survival, when deregulated and hyperactivated induces Alzheimer’s disease (AD) a...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Binukumar, B.K., Shukla, Varsha, Amin, Niranjana D., Bhaskar, Manju, Skuntz, Suzanne, Steiner, Joseph, Winkler, Dirk, Pelech, Steven L., Pant, Harish C.
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927891/
https://ncbi.nlm.nih.gov/pubmed/26444778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150412
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