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3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells
Eight 3-O-alkyl-2,3-dehydrosilibinins have been synthesized from commercially available silibinin through two synthetic approaches. A one-pot reaction, starting with aerobic oxidation of silibinin followed by direct alkylation of the phenolic hydroxyl group in the subsequent 2,3-dehydrosilibinin, fu...
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| Publicado en: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927305/ https://ncbi.nlm.nih.gov/pubmed/27261177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.05.069 |
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