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Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow

Endomitosis is a special type of mitosis in which only cytokinesis—the final step of the cell division cycle—is defective, resulting in polyploid cells. Although endomitosis is biologically important, its regulatory aspects remain elusive. Psychosine, a lysogalactosylceramide, prevents proper cytoki...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Watanabe, Hiroshi, Okahara, Kyohei, Naito-Matsui, Yuko, Abe, Mitsuhiro, Go, Shinji, Inokuchi, Jinichi, Okazaki, Toshiro, Kobayashi, Toshihide, Kozutsumi, Yasunori, Oka, Shogo, Takematsu, Hiromu
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927278/
https://ncbi.nlm.nih.gov/pubmed/27170180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0555
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