SLI1 (YGR212W) is a major gene conferring resistance to the sphingolipid biosynthesis inhibitor ISP-1, and encodes an ISP-1 N-acetyltransferase in yeast

ISP-1 (myriocin) is a potent inhibitor of serine palmitoyltransferase, the primary enzyme of sphingolipid biosynthesis, and is a useful tool for studying the biological functions of sphingolipids in both mammals and yeast (Saccharomyces cerevisiae). In a previous study, we cloned yeast multicopy sup...

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Detalhes bibliográficos
Main Authors: Momoi, Michiko, Tanoue, Daisuke, Sun, Yidi, Takematsu, Hiromu, Suzuki, Yusuke, Suzuki, Minoru, Suzuki, Akemi, Fujita, Tetsuro, Kozutsumi, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133791/
https://ncbi.nlm.nih.gov/pubmed/15025559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040108
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