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Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways

Sphingoid intermediates accumulate in response to a variety of stresses, including heat, and trigger cellular responses. However, the mechanism by which stress affects sphingolipid biosynthesis has yet to be identified. Recent studies in yeast suggest that sphingolipid biosynthesis is regulated thro...

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Detalhes bibliográficos
Main Authors: Sun, Yidi, Miao, Yansong, Yamane, Yukari, Zhang, Chao, Shokat, Kevan M., Takematsu, Hiromu, Kozutsumi, Yasunori, Drubin, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374756/
https://ncbi.nlm.nih.gov/pubmed/22535525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0209
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