Impaired Lysosomal Function Underlies Monoclonal Light Chain–Associated Renal Fanconi Syndrome

Monoclonal gammopathies are frequently complicated by kidney lesions that increase the disease morbidity and mortality. In particular, abnormal Ig free light chains (LCs) may accumulate within epithelial cells, causing proximal tubule (PT) dysfunction and renal Fanconi syndrome (RFS). To investigate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Luciani, Alessandro, Sirac, Christophe, Terryn, Sara, Javaugue, Vincent, Prange, Jenny Ann, Bender, Sébastien, Bonaud, Amélie, Cogné, Michel, Aucouturier, Pierre, Ronco, Pierre, Bridoux, Frank, Devuyst, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926980/
https://ncbi.nlm.nih.gov/pubmed/26614382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050581
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados