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JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium

Basal cells (BC) are the stem/progenitor cells of the human airway epithelium capable of differentiating into secretory and ciliated cells. Notch signaling activation increases BC differentiation into secretory cells, but the role of individual Notch ligands in regulating this process in the human a...

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Bibliografske podrobnosti
izdano v:Stem Cell Rev
Main Authors: Gomi, Kazunori, Staudt, Michelle R., Salit, Jacqueline, Kaner, Robert J., Heldrich, Jonna, Rogalski, Allison M., Arbelaez, Vanessa, Crystal, Ronald G., Walters, Matthew S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926772/
https://ncbi.nlm.nih.gov/pubmed/27216293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-016-9656-6
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