JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium

Basal cells (BC) are the stem/progenitor cells of the human airway epithelium capable of differentiating into secretory and ciliated cells. Notch signaling activation increases BC differentiation into secretory cells, but the role of individual Notch ligands in regulating this process in the human a...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev
Main Authors: Gomi, Kazunori, Staudt, Michelle R., Salit, Jacqueline, Kaner, Robert J., Heldrich, Jonna, Rogalski, Allison M., Arbelaez, Vanessa, Crystal, Ronald G., Walters, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926772/
https://ncbi.nlm.nih.gov/pubmed/27216293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-016-9656-6
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