Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels

Hepatitis C virus (HCV) substantially affects lipid metabolism, and remodeling of sphingolipids appears to be essential for HCV persistence in vitro. The aim of the current study is the evaluation of serum sphingolipid variations during acute HCV infection. We enrolled prospectively 60 consecutive p...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Grammatikos, Georgios, Dietz, Julia, Ferreiros, Nerea, Koch, Alexander, Dultz, Georg, Bon, Dimitra, Karakasiliotis, Ioannis, Lutz, Thomas, Knecht, Gaby, Gute, Peter, Herrmann, Eva, Zeuzem, Stefan, Mavromara, Penelope, Sarrazin, Christoph, Pfeilschifter, Josef
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926455/
https://ncbi.nlm.nih.gov/pubmed/27304952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060922
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