Investigation of NS3 Protease Resistance-Associated Variants and Phenotypes for the Prediction of Treatment Response to HCV Triple Therapy

Triple therapy of chronic hepatitis C virus (HCV) infection with boceprevir (BOC) or telaprevir (TVR) leads to virologic failure in many patients which is often associated with the selection of resistance-associated variants (RAVs). These resistance profiles are of importance for the selection of po...

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Veröffentlicht in:PLoS One
Hauptverfasser: Dietz, Julia, Rupp, Daniel, Susser, Simone, Vermehren, Johannes, Peiffer, Kai-Henrik, Filmann, Natalie, Bon, Dimitra, Kuntzen, Thomas, Mauss, Stefan, Grammatikos, Georgios, Perner, Dany, Berkowski, Caterina, Herrmann, Eva, Zeuzem, Stefan, Bartenschlager, Ralf, Sarrazin, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900565/
https://ncbi.nlm.nih.gov/pubmed/27281344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156731
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