Altered Levels of Sphingosine, Sphinganine and Their Ceramides in Atopic Dermatitis Are Related to Skin Barrier Function, Disease Severity and Local Cytokine Milieu

Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear whether these changes are intrinsic or initiated by inf...

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Publicado en:Int J Mol Sci
Main Authors: Jurakic Toncic, Ruzica, Jakasa, Ivone, Ljubojevic Hadzavdic, Suzana, Goorden, Susan MI, Ghauharali-van der Vlugt, Karen JM, Stet, Femke S, Balic, Anamaria, Petkovic, Mikela, Pavicic, Borna, Zuzul, Kristina, Marinovic, Branka, Kezic, Sanja
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139865/
https://ncbi.nlm.nih.gov/pubmed/32183011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21061958
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