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The end of the road for the tryptophan depletion concept in pregnancy and infection
We hypothesize that: (1) L-tryptophan (Trp) is greatly utilized and not depleted in pregnancy; (2) fetal tolerance is achieved in part through immunosuppressive kynurenine (Kyn) metabolites produced by the flux of plasma free (non-albumin-bound) Trp down the Kyn pathway; (3) the role of indoleamine...
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| Publicado en: | Clin Sci (Lond) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4926258/ https://ncbi.nlm.nih.gov/pubmed/27358028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20160153 |
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