ASXL1 plays an important role in erythropoiesis

ASXL1 mutations are found in a spectrum of myeloid malignancies with poor prognosis. Recently, we reported that Asxl1(+/−) mice develop myelodysplastic syndrome (MDS) or MDS and myeloproliferative neoplasms (MPN) overlapping diseases (MDS/MPN). Although defective erythroid maturation and anemia are...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Shi, Hui, Yamamoto, Shohei, Sheng, Mengyao, Bai, Jie, Zhang, Peng, Chen, Runze, Chen, Shi, Shi, Lihong, Abdel-Wahab, Omar, Xu, Mingjiang, Zhou, Yuan, Yang, Feng-Chun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926121/
https://ncbi.nlm.nih.gov/pubmed/27352931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28789
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