Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

Mitochondria are key players in aging and in the pathogenesis of age-related diseases. Recent mitochondrial transcriptome analyses revealed the existence of multiple small mRNAs transcribed from mitochondrial DNA (mtDNA). Humanin (HN), a peptide encoded in the mtDNA 16S ribosomal RNA region, is a ne...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Cobb, Laura J., Lee, Changhan, Xiao, Jialin, Yen, Kelvin, Wong, Richard G., Nakamura, Hiromi K., Mehta, Hemal H., Gao, Qinglei, Ashur, Carmel, Huffman, Derek M., Wan, Junxiang, Muzumdar, Radhika, Barzilai, Nir, Cohen, Pinchas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925829/
https://ncbi.nlm.nih.gov/pubmed/27070352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100943
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