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Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways
In this work, we examine the relationship between stress resistance and aging. We find that resistance to multiple types of stress peaks during early adulthood and then declines with age. To dissect the underlying mechanisms, we use C. elegans transcriptional reporter strains that measure the activa...
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Publicado no: | Aging (Albany NY) |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925828/ https://ncbi.nlm.nih.gov/pubmed/27053445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100939 |
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