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Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways

In this work, we examine the relationship between stress resistance and aging. We find that resistance to multiple types of stress peaks during early adulthood and then declines with age. To dissect the underlying mechanisms, we use C. elegans transcriptional reporter strains that measure the activa...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Dues, Dylan J., Andrews, Emily K., Schaar, Claire E., Bergsma, Alexis L., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925828/
https://ncbi.nlm.nih.gov/pubmed/27053445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100939
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