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Phase I and phase II objective response rates are correlated in pediatric cancer trials: an argument for better clinical trial efficiency
While many phase I trials report tumor response, formal analysis of efficacy is deferred to phase II. We reviewed paired phase I and II pediatric oncology trials to ascertain the relationship between phase I and II objective response (OR%). Single-agent phase I trials were paired with corresponding...
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Publicado no: | J Pediatr Hematol Oncol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925289/ https://ncbi.nlm.nih.gov/pubmed/27164535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000583 |
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