A Phase II Trial of Sorafenib in Metastatic Melanoma with Tissue Correlates

BACKGROUND: Sorafenib monotherapy in patients with metastatic melanoma was explored in this multi-institutional phase II study. In correlative studies the impact of sorafenib on cyclin D1 and Ki67 was assessed. METHODOLOGY/PRINCIPAL FINDINGS: Thirty-six patients treatment-naïve advanced melanoma pat...

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Hoofdauteurs: Ott, Patrick A., Hamilton, Anne, Min, Christina, Safarzadeh-Amiri, Sara, Goldberg, Lauren, Yoon, Joanne, Yee, Herman, Buckley, Michael, Christos, Paul J., Wright, John J., Polsky, David, Osman, Iman, Liebes, Leonard, Pavlick, Anna C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
Onderwerpen:
Clinical Trial
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012061/
https://ncbi.nlm.nih.gov/pubmed/21206909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015588
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