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Phase I and phase II objective response rates are correlated in pediatric cancer trials: an argument for better clinical trial efficiency

While many phase I trials report tumor response, formal analysis of efficacy is deferred to phase II. We reviewed paired phase I and II pediatric oncology trials to ascertain the relationship between phase I and II objective response (OR%). Single-agent phase I trials were paired with corresponding...

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Detalhes bibliográficos
Publicado no:J Pediatr Hematol Oncol
Main Authors: Yeh, Jonathan C., Huang, Peng, Cohen, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925289/
https://ncbi.nlm.nih.gov/pubmed/27164535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000583
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