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IL-4 sensitivity shapes the peripheral CD8(+) T cell pool and response to infection
Previous studies have revealed that a population of innate memory CD8(+) T cells is generated in response to IL-4, first appearing in the thymus and bearing high expression levels of Eomesodermin (Eomes) but not T-bet. However, the antigen specificity and functional properties of these cells is poor...
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Publicado no: | J Exp Med |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925014/ https://ncbi.nlm.nih.gov/pubmed/27298446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151359 |
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