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Transcriptional downregulation of S1pr1 is required for establishment of resident memory CD8(+) T cells
Cell-mediated immunity critically depends on lymphocyte localization at sites of infection. While some memory T cells recirculate, a distinct lineage (resident memory T cells; T(RM)) are embedded in non-lymphoid tissues (NLTs) and mediate potent protective immunity. However, the defining transcripti...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844557/ https://ncbi.nlm.nih.gov/pubmed/24162775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2745 |
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