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APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

CD95, a member of the death receptor family initiates a caspase-dependent apoptosis, when activated by its ligand CD95L, thought to negatively regulate erythrocyte production in the bone marrow. We have previously shown that CD95 is overexpressed in two thirds of patients with a lower risk myelodysp...

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發表在:Oncotarget
Main Authors: Raimbault, Anna, Pierre-Eugene, Cecile, Rouquette, Alexandra, Deudon, Celine, Willems, Lise, Chapuis, Nicolas, Mathis, Stephanie, Kunz, Claudia, Fricke, Harald, Kosmider, Olivier, Bardet, Valerie, Fontenay, Michaela
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924760/
https://ncbi.nlm.nih.gov/pubmed/26910909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7469
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