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APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

CD95, a member of the death receptor family initiates a caspase-dependent apoptosis, when activated by its ligand CD95L, thought to negatively regulate erythrocyte production in the bone marrow. We have previously shown that CD95 is overexpressed in two thirds of patients with a lower risk myelodysp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Raimbault, Anna, Pierre-Eugene, Cecile, Rouquette, Alexandra, Deudon, Celine, Willems, Lise, Chapuis, Nicolas, Mathis, Stephanie, Kunz, Claudia, Fricke, Harald, Kosmider, Olivier, Bardet, Valerie, Fontenay, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924760/
https://ncbi.nlm.nih.gov/pubmed/26910909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7469
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