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Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro

Glioblastoma is a disease characterized by rapid invasive tumour growth. Studies on the proapoptotic CD95/CD95L signalling pathway recently suggested a significant contribution of CD95 signalling towards the high degree of motility in glioma cells. Apogenix has developed APG101, a clinical phase II...

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Bibliografiske detaljer
Udgivet i:Anticancer Drugs
Main Authors: Merz, Christian, Strecker, Alexander, Sykora, Jaromir, Hill, Oliver, Fricke, Harald, Angel, Peter, Gieffers, Christian, Peterziel, Heike
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484665/
https://ncbi.nlm.nih.gov/pubmed/25850884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000237
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