SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

In this report, we show that malignant pleural mesothelioma (MPM) patients whose tumors express high levels of AKT1 exhibit a significantly worse prognosis, whereas no significant correlation with AKT3 expression is observed. We provide data that establish a phosphorylation independent role of AKT1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pinton, Giulia, Zonca, Sara, Manente, Arcangela G., Cavaletto, Maria, Borroni, Ester, Daga, Antonio, Jithesh, Puthen V., Fennell, Dean, Nilsson, Stefan, Moro, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924721/
https://ncbi.nlm.nih.gov/pubmed/26885609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7321
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