Agonist activation of estrogen receptor beta (ERβ) sensitizes malignant pleural mesothelioma cells to cisplatin cytotoxicity

BACKGROUND: Estrogen receptor (ER) β acts as a tumor suppressor in malignant mesotheliomas. METHODS: Here we explored the anti-proliferative and anti-tumorigenic efficacy of the selective ERβ agonist, KB9520, in human mesothelioma cell lines in vitro and in a mesothelioma mouse model in vivo. RESULT...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pinton, Giulia, Manente, Arcangela G, Daga, Antonio, Cilli, Michele, Rinaldi, Maurizio, Nilsson, Stefan, Moro, Laura
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2014
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197308/
https://ncbi.nlm.nih.gov/pubmed/25277603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-227
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