The molecular and clinical verification of therapeutic resistance via the p38 MAPK–Hsp27 axis in lung cancer

Treatment failure followed by relapse and metastasis in patients with non-small cell lung cancer is often the result of acquired resistance to cisplatin-based chemotherapy. A cancer stem cell (CSC)-mediated anti-apoptotic phenomenon is responsible for the development of drug resistance. The underlyi...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Chia-Lin, Chen, Su-Feng, Wu, Min-Zu, Jao, Shu-Wen, Lin, Yaoh-Shiang, Yang, Chin-Yuh, Lee, Tsai-Yu, Wen, Lian-Wu, Lan, Guo-Lun, Nieh, Shin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924714/
https://ncbi.nlm.nih.gov/pubmed/26872057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7306
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