Quercetin suppresses drug-resistant spheres via the p38 MAPK-Hsp27 apoptotic pathway in oral cancer cells.

BACKGROUND: Treatment failure in oral squamous cell carcinoma (OSCC) leading to local recurrence(s) and metastases is mainly due to drug resistance. Cancer stem cells (CSCs) are thought be responsible for the development of drug resistance. However, the correlations between CSCs, drug resistance, an...

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Главные авторы: Su-Feng Chen, Shin Nieh, Shu-Wen Jao, Chia-Lin Liu, Chien-Hua Wu, Yun-Ching Chang, Chin-Yuh Yang, Yaoh-Shiang Lin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3495857?pdf=render
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