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Opening of glibenclamide-sensitive K+ channels in follicular cells promotes Xenopus oocyte maturation.

The vasorelaxing K+ channel opener P1060 (a pinacidil analog), gonadotropins, and cAMP were shown to activate a glibenclamide-sensitive 86Rb+ efflux from fully grown follicle-enclosed Xenopus oocytes. Glibenclamide-sensitive K+ channels are located in follicular cells. Glibenclamide (i) depressed th...

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Detalhes bibliográficos
Main Authors: Wibrand, F, Honoré, E, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49243/
https://ncbi.nlm.nih.gov/pubmed/1594622
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