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ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release.

The adenohypophysis contains high-affinity binding sites for antidiabetic sulfonylureas that are specific blockers of ATP-sensitive K+ channels. The binding protein has a M(r) of 145,000 +/- 5000. The presence of ATP-sensitive K+ channels (26 pS) has been demonstrated by electrophysiological techniq...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bernardi, H, De Weille, J R, Epelbaum, J, Mourre, C, Amoroso, S, Slama, A, Fosset, M, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8433992/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1340
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