K+ channel openers activate brain sulfonylurea-sensitive K+ channels and block neurosecretion.
Vascular K+ channel openers such as cromakalim, nicorandil, and pinacidil potently stimulate 86Rb+ efflux from slices of substantia nigra. This 86Rb+ efflux is blocked by antidiabetic sulfonylureas, which are known to be potent and specific blockers of ATP-regulated K+ channels in pancreatic beta ce...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3489 |
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