Translational Features of Human Alpha 2b Interferon Production in Escherichia coli

The yield of human alpha 2b interferon in Escherichia coli was optimized by replacement of low-usage arginine codons located in the mRNA 5′ end. The differences observed among the various gene variants suggest that codon usage, Shine-Dalgarno-like sequences, and mRNA secondary structure contribute t...

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Bibliografische gegevens
Gepubliceerd in:Appl Environ Microbiol
Hoofdauteurs: Valente, C. A., Prazeres, D. M. F., Cabral, J. M. S., Monteiro, G. A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2004
Onderwerpen:
Physiology and Biotechnology
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492429/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15294846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.8.5033-5036.2004
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