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In Vivo Production of Artificial Nonribosomal Peptide Products in the Heterologous Host Escherichia coli

Nonribosomal peptide synthetases represent the enzymatic assembly lines for the biosynthesis of pharmacologically relevant natural peptides, e.g., cyclosporine, vancomycin, and penicillin. Due to their modular organization, in which every module accounts for the incorporation of a single amino acid,...

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Autori principali: Gruenewald, Stephan, Mootz, Henning D., Stehmeier, Per, Stachelhaus, Torsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC427719/
https://ncbi.nlm.nih.gov/pubmed/15184122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.6.3282-3291.2004
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