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Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides

The interaction between enzymes of a nonribosomal peptide synthetase (NRPS) complex relies on the interplay of compatible sets of donor and acceptor communication-mediating (COM) domains. Hence, these domains are essential for the formation of a defined biosynthetic template, thereby directing the s...

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Bibliografiske detaljer
Main Authors: Hahn, Martin, Stachelhaus, Torsten
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326170/
https://ncbi.nlm.nih.gov/pubmed/16407157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508409103
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