Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages

[Image: see text] Leoligin is a natural lignan found in Edelweiss (Leontopodium nivale ssp. alpinum). The aim of this study was to examine its influence on cholesterol efflux and to address the underlying mechanism of action. Leoligin increases apo A1- as well as 1% human plasma-mediated cholesterol...

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Publié dans:J Nat Prod
Auteurs principaux: Wang, Limei, Ladurner, Angela, Latkolik, Simone, Schwaiger, Stefan, Linder, Thomas, Hošek, Jan, Palme, Veronika, Schilcher, Nicole, Polanský, Ondřej, Heiss, Elke H., Stangl, Herbert, Mihovilovic, Marko D., Stuppner, Hermann, Dirsch, Verena M., Atanasov, Atanas G.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society and American Society of Pharmacognosy 2016
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924082/
https://ncbi.nlm.nih.gov/pubmed/27220065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00227
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